DNA Type 2 Diabetes Test
Fee Schedule for Year 2021
|Test Type||Testing Time||Fee|
|DNA Type 2 Diabetes Test||2 to 4 weeks||$7400Order Kit|
All orders received before 2pm are shipped out the same business day. All orders received after 2pm or on weekends or holidays are shipped out the following business day. 24/7 online status check and account management available for all tests.
Diabetes is a condition that affects how the body processes glucose (sugar). Glucose is the main source of fuel used in our bodies. Blood glucose levels are controlled by a hormone called insulin.
When glucose levels are high (e.g. after a meal), beta cells of the pancreas produce insulin, which signals for glucose to be stored. But, if this circuit fails, and blood glucose remains high, it leads to diabetes.
Type 1 and Type 2 diabetes
There are two main types of diabetes. Type 1 diabetes occurs when a person can’t make insulin, because their immune system has destroyed the insulin-producing beta cells in the pancreas.
People with type 2 diabetes make insulin, but their bodies don’t respond to it. As their blood glucose remains high, the pancreas tries to compensate by making extra insulin. Eventually the beta cells stop functioning because they are overworked and insulin is no longer produced. Type 2 diabetes can contribute to life threatening disorders, including heart disease, stroke, kidney failure and poor blood flow.
Risk factors for type 2 diabetes:
- Obesity, leading to insulin resistance
- Fat accumulation, primarily in the abdomen
- Lack of physical exercise
- Ethnicity (Africans and American Indians have a higher risk)
- Prediabetes (elevated blood sugar)
- Gestational diabetes
- Polycystic ovarian syndrome
- Genetic variation
DNA testing for type 2 diabetes
Genetic variations can affect our glucose and insulin levels, sensitivity to dietary fatty acids, and the way our body responds to insulin, resulting in increased risk of type 2 diabetes. Knowledge of genetic variants that increase your risk of type 2 diabetes allows you to make lifestyle changes today, to reduce your risk of this debilitating condition.
|ACC2||Reduced response to insulin|
|ADCY5||Inhibited secretion of insulin|
|FABP2, FTO||Increased uptake of saturated fats|
|ADIPOQ, CRY2, FADS1, G6PC2, GLUT2, MTNR1B, PROX1, TCF7L2||Increased fasting glucose levels|
|GCKR||Reduced fasting glucose levels|
|GCK, HNF4A||Reduced pancreatic beta cell function|
|GLIS3, IRS1, SLC30A8||Disrupted insulin production/signalling/storage|
|SHBG||Increased sex hormone binding globulin|
|MADD||Impaired proinsulin-to-insulin conversion|
|SOD2||Increased reactive oxygen species|
|HIF1A||Resistance to hypoxia|